NeuroMast Protocol® from InflammationMastery.com
NeuroMast Protocol® Next-Generation Biological Response Modification for Chronic Pain and Neuroinflammation, including Migraine, Fibromyalgia, CRPS, and Autism and more
NeuroMast Protocol ® has grown from Dr Vasquez's more than 35 years of study in health, medicine, and nutrition, and his university teaching in Orthopedics, Rheumatology, Evidence-Based Clinical Nutrition, and Principles and Practice of Functional Medicine. Dr Vasquez already had international expertise in the clinical management of common chronic pain conditions when an accident left him partially paralyzed and with CRPS—Complex Regional Pain Syndrome. Somewhat interestingly and ironically, DrV had already researched CRPS and had published on this topic in the top-level medical journal Nature Reviews Rheumatology. This very personal and painful experience forced DrV to go beyond his previous work, including what had recently been updated in the massive 1,200-page Inflammation Mastery: Textbook of Clinical Nutrition and Functional Medicine. For an inside glimpse into this experience and the fruits of this experience, take a look at VIDEO: How I cured myself of CRPS—Complex Regional Pain Syndrome, Sudeck Atrophy, Reflex Sympathetic Dystrophy: A Progressive Anthology.
Update: This page launched in 2021 and is being updated in 2026 to provide articles and videos. In the meanwhile, please see our listing of informative and relevant videos linked below as an extension of InflammationMastery.com:

NeuroMast Protocol® extends the pain-specific protocols in Inflammation Mastery by taking the science and effectiveness to the next level. More specifically, NeuroMast Protocol will update and extend Chapter 3 (pain management) and Chapter 5.2 (migraine, fibromyalgia, CRPS) with more details and therapeutics.
NeuroMast Protocol® Next-Generation Biological Response Modification for Chronic Pain and Neuroinflammation, including Migraine, Fibromyalgia, CRPS, and Autism and more
Why am I calling this “next generation”?
This work deserves to be called “next generation” because it is clearly above and beyond the current medical paradigm in pain management, which I have reviewed on an ongoing basis for many years and with which therefore I am more than sufficiently familiar and fluent. Current medical management of chronic pain conditions is a colossal failure, and this fact is universally acknowledged, except by those who profit from this ongoing failure.
See these recent video critiques of authoritative guidelines and positions, all of which guarantee clinical and financial failure of drug-dependent chronic pain management:
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VIDEO: Official Guidelines GUARANTEE FAILURE in CHRONIC PAIN per American Academy of Family Physicians 2021
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VIDEO: Decades of Stagnation in Migraine, CRPS, Pain Management: 30 years of nonstop medical propaganda
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VIDEO: SCIENCE OF PAIN MANAGEMENT from Harvard Medical School: Demonstration of medicine’s refusal to advance
Why am I calling this “Biological Response Modification”?
Medical “Biological Response Modification” is a somewhat meaningless phrase because it is overused and misused
As I mentioned in the video excerpted here (second video on this page), the phrase “Biological Response Modification” is a bit unfortunate because of the way the medical-drug profession has misused and abused it, applying it mostly to any drug or natural therapeutic that modifies immune responses especially against cancer but also autoimmunity. As such, they should have used the phrase “Immune Response Modification.” Beyond its abuse and misuse is its overuse—the medical profession uses the phrase too broadly and by so doing robs the phrase of its specificity and therefore its relevance. The “official definition” provided by the US NIH National Cancer Institute1 demonstrates how this term can be applied to anything and therefore—the way the medical profession abuses it—misapplied to everything
Nutritional-Integrative “Biological Response Modification” is an advanced paradigm that has periodically transformed disease treatment via qualitative “resets” of whole-body physiology. As I mentioned in the video (second video on this page), I use the phrase “Biological Response Modifier” more in alignment with the way that I began to understand it after first learning about it from Dr Jeffrey Bland in his 1994 presentation Advancement in Clinical Nutrition which I interpreted to imply metanutritional or at least “meta-expectation” physiological changes induced by therapeutic intervention, especially using nutrients alone but more commonly in combination.
That is exactly the clinical and scientific expectation of my new protocols including NeuroMast Protocol®
Alex Kennerly Vasquez DO ND DC (USA), prior Fellow of the American College of Nutrition (FACN), prior Overseas Fellow of the Royal Society of Medicine (RSM, London UK):
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{education} An award-winning clinician-scholar and founding Program Director of the world's first fully-accredited university-based graduate program in Human Nutrition and Functional Medicine, Dr Alex Vasquez is recognized internationally for his high intellectual and academic standards and for his detailed expertise spanning and interconnecting many topics in Medicine and Nutrition. Dr Vasquez holds three doctoral degrees as a graduate of University of Western States (Doctor of Chiropractic, 1996), Bastyr University (Doctor of Naturopathic Medicine, 1999), and University of North Texas Health Science Center, Texas College of Osteopathic Medicine (Doctor of Osteopathic Medicine, 2010). Dr Vasquez has completed thousands of hours of post-graduate and continuing education (certifications) in subjects including Obstetrics, Pediatrics, Basic and Advanced Disaster Life Support, Nutrition and Functional Medicine; while in the final year of medical school, Dr Vasquez completed a Pre-Doctoral Research Fellowship in Complementary and Alternative Medicine Research hosted by the US National Institutes of Health (NIH).
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{teaching, directing, organizing} Dr Vasquez has served in many teaching roles at the undergraduate, graduate, and doctorate levels in various accredited universities and colleges throughout the United States and has lectured internationally at the post-graduate level including accredited Continuing Medical Education (CME) for medical physicians. DrV was the founding Program Director of the world's first fully-accredited university-based graduate program in Human Nutrition and Functional Medicine, and almost-single-handedly orchestrated the entirety of the five-day 2013 International Conference on Human Nutrition and Functional Medicine.
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{books} Dr Vasquez is the author of more than ten textbooks, including Integrative Orthopedics (2004, 2007, 2012), Functional Medicine Rheumatology (2014), Musculoskeletal Pain: Expanded Clinical Strategies (commissioned and published by Institute for Functional Medicine, 2008), Chiropractic and Naturopathic Mastery of Common Clinical Disorders (2009), Integrative Medicine and Functional Medicine for Chronic Hypertension (2011), Brain Inflammation in Migraine and Fibromyalgia (2016), Antiviral Strategies and Immune Nutrition (2014), Autism, Dysbiosis, and the Gut-Brain Axis (2017) and the 1200-page Inflammation Mastery 4th Edition (2016) also published as a two-volume set titled Textbook of Clinical Nutrition and Functional Medicine. Dr Vasquez’s books are available internationally via bookstores such as BookDepository, Amazon, Barnes and Noble, ThriftBooks, AbeBooks, BetterWorldBooks, WaterStonesBooks.
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{journals—publishing} "DrV" has written approximately 100 letters and articles for professional magazines and medical journals including:
1. TheLancet .com (online x1)
2. Journal of the American Medical Association (JAMA)
3. Journal of the American Osteopathic Association (JAOA)
4. British Medical Journal (BMJ: online x3, print x1)
5. Journal of Orthomolecular Medicine (x3)
6. Nature Reviews Rheumatology
7. Annals of the New York Academy of Sciences
8. Arthritis & Rheumatism—Official Journal of the American College of Rheumatology
9. Journal of Clinical Endocrinology and Metabolism
10. Alternative Therapies in Health and Medicine (x2)
11. Current Asthma and Allergy Reports
12. Complementary Therapies in Clinical Practice
13. Annals of Pharmacotherapy
14. Nutritional Perspectives (x11)
15. Journal of Manipulative and Physiological Therapeutics (JMPT)
16. Original Internist (x3)
17. Integrative Medicine (x4)
18. Holistic Primary Care
19. Journal of Restorative Medicine
20. Dynamic Chiropractic (x3)
21. Naturopathic Doctor News & Review (x2)
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{journals—reviewing and Editing} Dr Vasquez served as the founding Editor of Naturopathy Digest, founding Editor (2013-) of International Journal of Human Nutrition and Functional Medicine and Editor (2018-2019) of Journal of Orthomolecular Medicine and has previously served on the Review Boards for Acta Neuropsychiatrica, Journal of Pain Research, Autoimmune Diseases, PLOS One, Alternative Therapies in Health and Medicine, Neuropeptides, International Journal of Clinical Medicine, Journal of Inflammation Research, BMC Complementary and Alternative Medicine (all PubMed/Medline indexed), Integrated Blood Pressure Control, Journal of Biological Physics and Chemistry, Chiropractic Journal of Australia, Journal of Chiropractic Humanities, and Journal of Naturopathic Medicine,
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{high-level profitability} Dr Vasquez has spearheaded low-resource high-quality high-profit educational programs that were instantly profitable to several million dollars; Dr Vasquez has created several products for the nutrition industry with multi-million-dollar valuationsvaluations, including the popularization of higher-dose vitamin D supplementation with his 2004 “vitamin D paradigm shift” followed by publications in Journal of the American Medical Association (JAMA), British Medical Journal (BMJ), The Lancet (website), and Journal of Clinical Endocrinology and Metabolism.
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{bio} Dr Vasquez lectures internationally to healthcare professionals, has a consulting practice and service for doctors and patients, and constantly reviews research to produce new articles, videos, educational materials, and innovative product formulations. Dr Vasquez served as Director of Medical Board of Advisors, senior consultant, product designer, writer and lecturer for Biotics Research Corporation (Texas) from for 18 years (2004-2022) and continues producing educational materials and products for the nutraceutical market. Dr Vasquez has lived in Colombia, throughout the United States (Houston, Fort Worth, Austin, Miami, Pittsburgh, Seattle, Gainesville GA, Portland OR) and Spain (Barcelona, Tarragona, San Sebastian, Ourense).
Update: This page is being updated in 2026 to provide articles and videos. In the meanwhile, please see our listing of informative and relevant videos linked below as an extension of InflammationMastery.com: